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Onchain Execution: How Institutions Are Trading in DeFi Markets

Joint with Uniswap Labs on the custody, compliance and execution stack behind institutional DeFi.

Jan 13, 2026
Market Structure
DeFi
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The institutional conversation around trading onchain has shifted from "if" to "how" over the past 18-24 months. What was once viewed as experimental infrastructure for retail traders now represents a strategic venue for institutional execution, one that offers transparent liquidity, atomic settlement, and competitive pricing.

The shift to onchain trading has been enabled by fundamental improvements across custody, compliance, and execution infrastructure. Solutions like Fireblocks and Anchorage Digital now provide institutional-grade custody that integrates natively with DeFi protocols. Trading platforms have evolved to offer unified, API-driven access that fits existing institutional workflows. The result: institutions can now execute onchain without disrupting operational processes or compromising on the standards they expect from traditional venues.

Onchain Execution: How Institutions Are Trading in DeFi Markets

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